1. Miyazawa M, Takatori H, Okafuji H, Hayashi T, Toyama T, Yamada S, Kitamura K, Arai K, ★Sakai Y, Yamashita T, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Efficacy of a novel self-expandable metal stent with dumbbell-shaped flare ends for distal biliary obstruction due to unresectable pancreatic cancer. Sci Rep. 2022 Dec 6;12(1):21100. doi: 10.1038/s41598-022-25186-2. PMID: 36473910
  2. Li S, Mizukoshi E, Kawaguchi K, Miura M, Nishino M, Shimakami T, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Honda M, Kaneko S. Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals. Int J Mol Sci. 2022 Oct 1;23(19):11623. doi: 10.3390/ijms231911623. PMID: 36232928
  3. Li R, Okada H, Yamashita T, Nio K, Chen H, Li Y, Shimakami T, Takatori H, Arai K, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition. Int J Mol Sci. 2022 Jul 27;23(15):8305. doi: 10.3390/ijms23158305.
  4. Sumiyadorj A, Murai K, Shimakami T, Kuroki K, Nishikawa T, Kakuya M, Yamada A, Wang Y, Ishida A, Shirasaki T, Kawase S, Li YY, Okada H, Nio K, Kawaguchi K, Yamashita T, ★Sakai Y, Duger D, Mizukoshi E, Honda M, Kaneko S. A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes. Hepatol Commun. 2022 Sep;6(9):2441-2454. doi: 10.1002/hep4.2018.
  5. Mizukoshi E, Nakagawa H, Tamai T, Kitahara M, Fushimi K, Nio K, Terashima T, Iida N, Arai K, Yamashita T, Yamashita T, ★Sakai Y, Honda M, Kaneko S. Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8 + T cells. Nat Commun. 2022 Jun 3;13(1):3123. doi: 10.1038/s41467-022-30861-z.
  6. Suda T, Yamashita T, Sunagozaka H, Okada H, Nio K, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma. Int J Mol Sci. 2022 Mar 3;23(5):2801. doi: 10.3390/ijms23052801.
  7. Okafuji H, Iida N, Kitamura K, Seishima J, Wang Z, Yutani M, Yoshio T, Yamashita T, ★Sakai Y, Honda M, Yamashita T, Fujinaga Y, Shinkura R, Hamaguchi Y, Mizukoshi E, Kaneko S. Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut. Digestion. 2022;103(4):269-286. doi: 10.1159/000522039.
  8. Chen H, Nio K, Tang H, Yamashita T, Okada H, Li Y, Doan PTB, Li R, Lv J, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S.　BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma. Int J Mol Sci. 2022 Jan 27;23(3):1475. doi: 10.3390/ijms23031475.
  9. Iida N, Mizukoshi E, Yamashita T, Yutani M, Seishima J, Wang Z, Arai K, Okada H, Yamashita T, ★Sakai Y, Masuo Y, Agustina R, Kato Y, Fujinaga Y, Oshima M, Honda M, Lebreton F, Gilmore MS, Kaneko S. Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis. Nat Cancer. 2021 Oct;2(10):1039-1054. doi: 10.1038/s43018-021-00251-3.
  10. Yano M, Nasti A, Seki A, Ishida K, Yamato M, Inui H, Ogawa N, Inagaki S, Ho TTB, Kawaguchi K, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Inoue O, Takashima S, Usui S, Takamura M, Honda M, Wada T, Kaneko S, ★Sakai Y. Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair. Regen Ther. 2021 Dec 3;18:497-507. doi: 10.1016/j.reth.2021.11.005.
  11. ★Sakai Y, Nasti A, Takeshita Y, Okumura M, Kitajima S, Honda M, Wada T, Nakamura S, Takamura T, Tamura T, Matsubara K, Kaneko S. Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up. Sci Rep. 2021 Aug 16;11(1):16564. doi: 10.1038/s41598-021-96078-0.
  12. Kawaguchi K, ★Sakai Y, Terashima T, Shimode T, Seki A, Orita N, Takeshita Y, Shimakami T, Takatori H, Arai K, Kitamura K, Yamashita T, Yamashita T, Takamura M, Mizukoshi E, Takamura T, Honda M, Wada T, Kaneko S. Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease. Medicine (Baltimore). 2021 Aug 6;100(31):e26835. doi: 10.1097/MD.0000000000026835.
  13. Matsukawa H, Iida N, Kitamura K, Terashima T, Seishima J, Makino I, Kannon T, Hosomichi K, Yamashita T, ★Sakai Y, Honda M, Yamashita T, Mizukoshi E, Kaneko S. Dysbiotic gut microbiota in pancreatic cancer patients form correlation networks with the oral microbiota and prognostic factors. Am J Cancer Res. 2021 Jun 15;11(6):3163-3175.
  14. Shirasaki T, Murai K, Honda M, Okada H, Innami Y, Yamada A, Shimakami T, Kawaguchi K, Yamashita T, ★Sakai Y, Kaneko S. Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice. Sci Rep. 2021 Jun 22;11(1):13021. doi: 10.1038/s41598-021-92128-9.
  15. Ishida K, Seki A, Kawaguchi K, Nasti A, Yamato M, Inui H, Komura T, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Honda M, Wada T, Harada K, Kaneko S, ★Sakai Y. Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice. Stem Cell Res. 2021 Jul;54:102425. doi: 10.1016/j.scr.2021.102425.
  16. ★Sakai Y, Fukunishi S, Takamura M, Kawaguchi K, Inoue O, Usui S, Takashima S, Seki A, Asai A, Tsuchimoto Y, Nasti A, Bich Ho TT, Imai Y, Yoshimura K, Murayama T, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Honda M, Wada T, Harada K, Higuchi K, Kaneko S. Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy. Regen Ther. 2021 May 21;18:97-101. doi: 10.1016/j.reth.2021.04.003.
  17. Chen H, Nio K, Yamashita T, Okada H, Li R, Suda T, Li Y, Doan PTB, Seki A, Nakagawa H, Toyama T, Terashima T, Iida N, Shimakami T, Takatori H, Kawaguchi K, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. BMP9-ID1 signaling promotes EpCAM-positive cancer stem cell properties in hepatocellular carcinoma. Mol Oncol. 2021 Aug;15(8):2203-2218. doi: 10.1002/1878-0261.12963.
  18. Kida A, Mizukoshi E, Kido H, Toyama T, Terashima T, Arai K, Yamashita T, Fushimi K, Yamashita T, ★Sakai Y, Honda M, Uchiyama A, Sakai A, Shimizu K, Kaneko S. The characteristics of the immune cell profiles in peripheral blood in cholangiocarcinoma patients. Hepatol Int. 2021 Jun;15(3):695-706. doi: 10.1007/s12072-021-10177-8.
  19. Yamashita T, Koshikawa N, Shimakami T, Terashima T, Nakagawa M, Nio K, Horii R, Iida N, Kawaguchi K, Arai K, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kitao A, Kobayashi S, Takahara S, Imai Y, Yoshimura K, Murayama T, Nakamoto Y, Yoshida E, Yoshimura T, Seiki M, Kaneko S. Serum laminin γ2 monomer as a novel diagnostic and predictive biomarker for hepatocellular carcinoma. Hepatology. 2021 Feb 20. doi: 10.1002/hep.31758.
  20. Takata N, Ishii KA, Takayama H, Nagashimada M, Kamoshita K, Tanaka T, Kikuchi A, Takeshita Y, Matsumoto Y, Ota T, Yamamoto Y, Yamagoe S, Seki A, ★Sakai Y, Kaneko S, Takamura T. LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH. Sci Rep. 2021 Jan 12;11(1):555. doi: 10.1038/s41598-020-80689-0.
  21. Ho TTB, Nasti A, Seki A, Komura T, Inui H, Kozaka T, Kitamura Y, Shiba K, Yamashita T, Yamashita T, Mizukoshi E, Kawaguchi K, Wada T, Honda M, Kaneko S, ★Sakai Y. Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis. J Immunother Cancer. 2020 Nov;8(2):e001367. doi: 10.1136/jitc-2020-001367.
  22. Terashima T, Yamashita T, Takata N, Takeda Y, Kido H, Iida N, Kitahara M, Shimakami T, Takatori H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Safety and efficacy of sorafenib followed by regorafenib or lenvatinib in patients with hepatocellular carcinoma. Hepatol Res. 2021 Feb;51(2):190-200. doi: 10.1111/hepr.13588.
  23. Kumai T, Mizukoshi E, Hashiba T, Nakagawa H, Kitahara M, Miyashita T, Mochizuki T, Goto S, Kamigaki T, Takimoto R, Yamashita T, ★Sakai Y, Yamashita T, Honda M, Tomita K, Kaneko S. Effect of adoptive T-cell immunotherapy on immunological parameters and prognosis in patients with advanced pancreatic cancer. Cytotherapy. 2021 Feb;23(2):137-145. doi: 10.1016/j.jcyt.2020.08.001.
  24. Shimizu Y, Arai K, Yamashita T, Yamashita T, Shimakami T, Kawaguchi K, Kitamura K, ★Sakai Y, Mizukoshi E, Honda M, Kitao A, Kozaka K, Kobayashi S, Kaneko S. Direct-Acting Antiviral Agents Reduce the Risk of Malignant Transformation of Hepatobiliary Phase-Hypointense Nodule without Arterial Phase Hyperenhancement to Hepatocellular Carcinoma on Gd-EOB-DPTA-Enhanced Imaging in the Hepatitis C Virus-Infected Liver. Liver Cancer. 2020 Jun;9(3):261-274. doi: 10.1159/000504889.
  25. 大江弓起子,　佐藤晃一,　高山知子,　竹本賢一,　大江宏康,　森　三佳,　★酒井佳夫,　和田隆志. Fabry病における尿沈渣検査の重要性. Importance of Urine Sediment Analysis in Fabry Disease. 医療検査と自動化 vol.45 o.3 2020 p.264-268
  26. Sugimoto S, Terashima T, Yamashita T, Iida N, Kitahara M, Hodo Y, Shimakami T, Takatori H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Shirota Y, Sato K, Mizukoshi E, Honda M, Harada K, Kaneko S. Tumor lysis syndrome in a patient with metastatic melanoma treated with nivolumab. Clin J Gastroenterol. 2020 Oct;13(5):935-939. doi: 10.1007/s12328-020-01164-x.
  27. Miura M, Mizukoshi E, Hashiba T, Kitahara M, Miyashita T, Mochizuki T, Goto S, Kamigaki T, Takimoto R, Yamashita T, ★Sakai Y, Yamashita T, Honda M, Kaneko S. Effects of adaptive immune cell therapy on the immune cell profile in patients with advanced gastric cancer. Cancer Med. 2020 Jul;9(14):4907-4917. doi: 10.1002/cam4.3152.
  28. Kitabayashi J, Shirasaki T, Shimakami T, Nishiyama T, Welsch C, Funaki M, Murai K, Sumiyadorj A, Takatori H, Kitamura K, Kawaguchi K, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S; Hokuriku Liver Study Group. Upregulation of the Long Non-Coding RNA HULC by Hepatitis C Virus and its Regulation of Viral Replication. J Infect Dis. 2020 Jun 9;jiaa325. doi: 10.1093/infdis/jiaa325.
  29. Kitahara M, Mizukoshi E, Terashima T, Nakagawa H, Horii R, Iida N, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Honda M, Nakamoto Y, Kaneko S. Safety and Long-Term Outcome of Intratumoral Injection of OK432-Stimulated Dendritic Cells for Hepatocellular Carcinomas After Radiofrequency Ablation. Transl Oncol. 2020 Jul;13(7):100777. doi: 10.1016/j.tranon.2020.100777.
  30. Miyazawa M, Takatori H, Kawaguchi K, Kitamura K, Arai K, Matsuda K, Urabe T, Inamura K, Komura T, Mizuno H, Fuchizaki U, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Management of biliary stricture in patients with IgG4-related sclerosing cholangitis. PLoS One. 2020 Apr 30;15(4):e0232089. doi: 10.1371/journal.pone.0232089.
  31. Terashima T, Yamashita T, Takata N, Toyama T, Shimakami T, Takatori H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Comparative analysis of liver functional reserve during lenvatinib and sorafenib for advanced hepatocellular carcinoma. Hepatol Res. 2020 Jul;50(7):871-884. doi: 10.1111/hepr.13505.
  32. Terashima T, Honda M, Toyama T, Shimakami T, Shimizu R, Takatori H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. IL-28B variant as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy. J Gastroenterol Hepatol. 2020 Oct;35(10):1813-1820. doi: 10.1111/jgh.15035.
  33. Hashiba T, Yamashita T, Okada H, Nio K, Hayashi T, Asahina Y, Hayashi T, Terashima T, Iida N, Takatori H, Shimakami T, Kawaguchi K, Arai K, ★Sakai Y, Yamashita T, Mizukoshi E, Takamura H, Ohta T, Honda M, Kaneko S. Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol. 2020;10(2):269-285. doi: 10.1016/j.jcmgh.2020.02.009.
  34. Seike T, Mizukoshi E, Yamada K, Okada H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Yamashita T, ★Sakai Y, Honda M, Harada K, Kaneko S. Fatty acid-driven modifications in T-cell profiles in non-alcoholic fatty liver disease patients. J Gastroenterol. 2020 Jul;55(7):701-711. doi: 10.1007/s00535-020-01679-7.
  35. Nishikawa T, Nagata N, Shimakami T, Shirakura T, Matsui C, Ni Y, Zhuge F, Xu L, Chen G, Nagashimada M, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S, Ota T. Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice. Sci Rep. 2020 Jan 21;10(1):815. doi: 10.1038/s41598-020-57784-3.
  36. Hayashi T, Takatori H, Horii R, Nio K, Terashima T, Iida N, Kitahara M, Shimakami T, Arai K, Kitamura K, Kawaguchi K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Toyama T, Okumura K, Kozaka K, Kaneko S. Danaparoid sodium-based anticoagulation therapy for portal vein thrombosis in cirrhosis patients. BMC Gastroenterol. 2019 Dec 16;19(1):217. doi: 10.1186/s12876-019-1140-8.
  37. Seishima J, Iida N, Kitamura K, Yutani M, Wang Z, Seki A, Yamashita T, ★Sakai Y, Honda M, Yamashita T, Kagaya T, Shirota Y, Fujinaga Y, Mizukoshi E, Kaneko S. Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host. Genome Biol. 2019 Nov 25;20(1):252. doi: 10.1186/s13059-019-1879-9.
  38. Iwata Y, Sakai N, Yoneda I, Satou K, Furuichi K, Senda Y, Sakai-Takemori Y, Wada T, Fujita S, Ogura H, Sato K, Minami T, Yamaguchi K, Kitajima S, Toyama T, Yamamura Y, Miyagawa T, Hara A, Shimizu M, ★Sakai Y, Ikeo K, Shichino S, Ueha S, Nakajima T, Matsushima K, Wada T. The increased frequency of methicillin-resistant Staphylococcus aureus with low MIC of beta-lactam antibiotics isolated from hospitalized patients. J Infect Chemother. 2020 Jun;26(6):604-610. doi: 10.1016/j.jiac.2020.01.016. Epub 2020 Feb 22.PMID: 32094050
  39. ★Sakai Y, Fukunishi S, Takamura M, Inoue O, Takashima S, Usui S, Seki A, Nasti A, Ho TTB, Kawaguchi K, Asai A, Tsuchimoto Y, Yamashita T, Yamashita T, Mizukoshi E, Honda M, Imai Y, Yoshimura K, Murayama T, Wada T, Harada K, Higuchi K, Kaneko S. Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial. JMIR Res Protoc 2020 Mar 31;9(3):e17904. doi: 10.2196/17904.
  40. Tamai T, Mizukoshi E, Kumagai M, Terashima T, Iida N, Kitahara M, Shimakami T, Kitamura K, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Honda M, Fushimi K, Kaneko S. A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma. Sci Rep. 2020 Mar 4;10(1):4021. doi: 10.1038/s41598-020-60843-4. PMID: 32132566.
  41. ★酒井佳夫,　鷹取　元,　梶　喜一郎,　島上哲郎,　北村和哉,　川口和紀,　荒井邦明,　山下太郎,　山下竜也,　水腰英四朗,　本多政夫,　金子周一. 心臓マッサージ後に生じた食道粘膜下血腫の1例. Endscopic Forum for digestive disease. Vol.35 (2):113-117,2019. （2019年12月）
  42. Terashima T, Yamashita T, Toyama T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Liver Cancer. 2019 Mar;8(2):130-139. doi: 10.1159/000489505.
  43. Murai K, Honda M, Shirasaki T, Shimakami T, Omura H, Misu H, Kita Y, Takeshita Y, Ishii KA, Takamura T, Urabe T, Shimizu R, Okada H, Yamashita T, ★Sakai Y, Kaneko S. Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity. Cell Host Microbe. 2019 Apr 10;25(4):588-601.e7. doi: 10.1016/j.chom.2019.02.015.
  44. Yonejima A, Mizukoshi E, Tamai T, Nakagawa H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Okada H, Yamashita T, ★Sakai Y, Honda M, Kaneko S. Characteristics of impaired dendritic cell function in patients with hepatitis B virus infection. Hepatology. 2019 Jul;70(1):25-39. doi: 10.1002/hep.30637.
  45. Yamato M, ★Sakai Y, Mochida H, Kawaguchi K, Takamura M, Usui S, Seki A, Mizukoshi E, Yamashita T, Yamashita T, Ishida K, Nasti A, Tuyen HTB, Komura T, Yoshida K, Wada T, Honda M, Kaneko S. Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation. J Gastroenterol Hepatol. 2019 Aug;34(8):1432-1440. doi: 10.1111/jgh.14647. Epub 2019 Mar 31. PMID: 30828861.
  46. Fujinaga H, ★Sakai Y, Yamashita T, Arai K, Terashima T, Komura T, Seki A, Kawaguchi K, Nasti A, Yoshida K, Wada T, Yamamoto K, Kume K, Hasegawa T, Takata T, Honda M, Kaneko S. Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation. Int J Radiat Biol. 2019 May;95(5):571-579. doi: 10.1080/09553002.2019.1558297. PMID: 30557072.
  47. ★Sakai Y, Honda M, Matsui S, Komori O, Murayama T, Fujiwara T, Mizuno M, Imai Y, Yoshimura K, Nasti A, Wada T, Iida N, Kitahara M, Horii R, Tamai T, Nishikawa M, Okafuji H, Mizukoshi E, Yamashita T, Yamashita T, Arai K, Kitamura K, Kawaguchi K, Takatori H, Shimakami T, Terashima T, Hayashi T, Nio K, Kaneko S, Hokuriku Liver Study Group. Development of novel diagnostic system for pancreas cancer including early stages measuring mRNA of whole blood cells. Cancer Sci. 2019 Apr;110(4):1364-1388. doi: 10.1111/cas.13971.
  48. ★Sakai Y, Miyazawa M, Komura T, Yamada T, Nasti A, Yoshida K, Takabatake H, Yamato M, Yamashita T, Yamashita T, Mizukoshi E, Okuzono M, Ho TTB, Kawaguchi K, Wada T, Honda M, Kaneko S. Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models. Cancer Sci. 2019 Mar;110(3):903-912. doi: 10.1111/cas.13944.
  49. Orita N, Shimakami T, Sunagozaka H, Horii R, Nio K, Terashima T, Iida N, Kitahara M, Takatori H, Kawaguchi K, Kitamura K, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Three renal failure cases successfully treated with ombitasvir/paritaprevir/ritonavir for genotype 1b hepatitis C virus reinfection after liver transplantation. Clin J Gastroenterol. 2019 Feb;12(1):63-70. doi: 10.1007/s12328-018-0884-y.
  50. Wang Z, Kawaguchi K, Honda M, Hashimoto S, Shirasaki T, Okada H, Orita N, Shimakami T, Yamashita T, ★Sakai Y, Mizukoshi E, Murakami S, Kaneko S. Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation. Sci Rep. 2019 Feb 7;9(1):1621. doi: 10.1038/s41598-018-38139-5.
  51. Kanno M, Kawaguchi K, Honda M, Horii R, Takatori H, Shimakami T, Kitamura K, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E,Kaneko S. Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis. J Gastroenterol. 2019 Jun;54(6):549-557. doi: 10.1007/s00535-019-01551-3.
  52. Shirasaki T, Honda M, Yamashita T, Nio K, Shimakami T, Shimizu R, Nakasyo S, Murai K, Shirasaki N, Okada H, ★Sakai Y, Sato T, Suzuki T, Yoshioka K, Kaneko S. The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication. Sci Rep. 2018 Sep 3;8(1):13143. doi: 10.1038/s41598-018-31421-6.
  53. Komura T, Yano M, Miyake A, Takabatake H, Miyazawa M, Ogawa N, Seki A, Honda M, Wada T, Matsui S, Kaneko S, ★Sakai Y. Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood. Can J Gastroenterol Hepatol. 2018 Jun 11;2018:7436205. doi: 10.1155/2018/7436205.
  54. Terashima T, Yamashita T, Sunagozaka H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: Prospects for regorafenib therapy. Hepatol Res. 2018 Nov;48(12):956-966. doi: 10.1111/hepr.13196.
  55. Wang Z, Kawaguchi K, Honda M, ★Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Distinct notch signaling expression patterns between nucleoside and nucleotide analogues treatment for hepatitis B virus infection. Biochem Biophys Res Commun. 2018 Jun 27;501(3):682-687. doi: 10.1016/j.bbrc.2018.04.236.
  56. Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S. Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B. J Gastroenterol. 2018 Jun;53(6):740-751. doi: 10.1007/s00535-017-1386-2.
  57. Murai K, Shirasaki T, Honda M, Shimizu R, Shimakami T, Nakasho S, Shirasaki N, Okada H, ★Sakai Y, Yamashita T, Kaneko S. Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro. Int J Mol Sci. 2018 Jan 23;19(2). pii: E108. doi: 10.3390/ijms19020108.
  58. Hayashi T, Yamashita T, Terashima T, Suda T, Okada H, Asahina Y, Hayashi T, Hara Y, Nio K, Sunagozaka H, Takatori H, Arai K, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study. BMC Cancer. 2017 Dec 19;17(1):870. doi: 10.1186/s12885-017-3889-x.
  59. Funaki M, Kitabayashi J, Shimakami T, Nagata N, ★Sakai Y, Takegoshi K, Okada H, Murai K, Shirasaki T, Oyama T, Yamashita T, Ota T, Takuwa Y, Honda M, Kaneko S. Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo. Sci Rep. 2017 Dec 5;7(1):16978. doi: 10.1038/s41598-017-17285-2.
  60. Miyazawa M, Takatori H, Shimakami T, Kawaguchi K, Kitamura K, Arai K, Matsuda K, Sanada T, Urabe T, Inamura K, Kagaya T, Mizuno H, Fuchizaki U, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Prognosis of type 1 autoimmune pancreatitis after corticosteroid therapy-induced remission in terms of relapse and diabetes mellitus. PLoS One. 2017 Nov 22;12(11):e0188549. doi: 10.1371/journal.pone.0188549.
  61. Komura T, Takabatake H, Harada K, Yamato M, Miyazawa M, Yoshida K, Honda M, Wada T, Kitagawa H, Ohta T, Kaneko S, ★Sakai Y. Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma. Cancer Sci. 2017 Nov;108(11):2122-2129. doi: 10.1111/cas.13396.
  62. Nasti A, ★Sakai Y, Seki A, Buffa GB, Komura T, Mochida H, Yamato M, Yoshida K, Ho TTB, Takamura M, Usui S, Wada T, Honda M, Kaneko S. The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells. Eur J Immunol. 2017 Dec;47(12):2163-2174. doi: 10.1002/eji.201646835.
  63. Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma. Liver Cancer. 2017 Jun;6(3):236-249. doi: 10.1159/000472262.
  64. Okada H, Takabatake R, Honda M, Takegoshi K, Yamashita T, Nakamura M, Shirasaki T, ★Sakai Y, Shimakami T, Nagata N, Takamura T, Tanaka T, Kaneko S. Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet. Oncotarget. 2017 Jun 20;8(25):39978-39993. doi: 10.18632/oncotarget.18116.
  65. 大和 雅敏, 荒井 邦明, 鷹取 元, 島上 哲朗, 山下 太郎, ★酒井 佳夫, 山下 竜也, 水腰 英四郎, 本多 政夫, 金子 周一.　HCV関連腎症にdirect-acting antiviral agentsが奏功し，大量胸腹水がコントロールされたC型肝硬変の1例.　日本消化器病学会雑誌　2017 年       114 巻   6 号       p. 1031-1038
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  71. Kawaguchi K, Honda M, Yamashita T, Okada H, Shirasaki T, Nishikawa M, Nio K, Arai K, ★Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer. Am J Pathol. 2016 Aug;186(8):2055-67. doi: 10.1016/j.ajpath.2016.04.011.
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  77. Honda M, Shirasaki T, Terashima T, Kawaguchi K, Nakamura M, Oishi N, Wang X, Shimakami T, Okada H, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma. J Infect Dis. 2016 Apr 1;213(7):1096-106. doi: 10.1093/infdis/jiv572.
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  82. 清水吉晃, 北原征明, 山下竜也, 荒井邦明, 山下太郎, 加賀谷尚史, ★酒井佳夫, 水腰英四郎, 本多政夫, 金子周一.  Basedow病を合併し肝不全に至ったB型慢性肝炎の1例. 日本消化器病学会雑誌 112(1): 94 -100 201.
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  84. Okada H, Honda M, Campbell JS, Takegoshi K, ★Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S. Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice. Cancer Sci. 2015 Sep;106(9):1143-52. doi: 10.1111/cas.12730.
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  89. Terashima T, Yamashita T, Iida N, Yamashita T, Nakagawa H, Arai K, Kitamura K, Kagaya T, ★Sakai Y, Mizukoshi E, Honda M, Kaneko S. Blood neutrophil to lymphocyte ratio as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy. Hepatol Res. 2015 Sep;45(9):949-959. doi: 10.1111/hepr.12436.
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  93. Shirasaki T, Honda M, Shimakami T, Murai K, Shiomoto T, Okada H, Takabatake R, Tokumaru A, ★Sakai Y, Yamashita T, Lemon SM, Murakami S, Kaneko S. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway. Hepatology. 2014 Nov;60(5):1519-30. doi: 10.1002/hep.27277.
  94. Nakade Y, Toyama T, Furuichi K, Kitajima S, Ohkura N, Sagara A, Shinozaki Y, Hara A, Kitagawa K, Shimizu M, Iwata Y, Oe H, Nagahara M, Horita H, ★Sakai Y, Kaneko S, Wada T. Impact of kidney function and urinary protein excretion on pulmonary function in Japanese patients with chronic kidney disease. Clin Exp Nephrol. 2014 Oct;18(5):763-9. doi: 10.1007/s10157-013-0920-7.
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  97. 山田和俊, 北村和哉, 丹尾幸樹, 島上哲朗, 荒井邦明, 柿木嘉平太, 山下太郎, ★酒井佳夫, 水腰英四郎, 金子周一. 食道静脈瘤に対する内視鏡的硬化療法後に第Ⅴ因子欠損症を来した1例. 日本消化器内視鏡学会雑誌. 56巻3号　451-456頁　2014（3月）
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  102. Honda M, Yamashita T, Yamashita T, Arai K, ★Sakai Y, Sakai A, Nakamura M, Mizukoshi E, Kaneko S. Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma.  BMC Cancer. 2013 Apr 15;13:191. doi: 10.1186/1471-2407-13-191.
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  123. Takata Y, Nakamoto Y, Nakada A, Terashima T, Arihara F, Kitahara M, Kakinoki K, Arai K, Yamashita T, ★Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. Frequency of CD45RO+ subset in CD4+CD25(high) regulatory T cells associated with progression of hepatocellular carcinoma. Cancer Lett. 2011 Aug 28;307(2):165-73. doi: 10.1016/j.canlet.2011.03.029.
  124. Mizukoshi E, Nakamoto Y, Arai K, Yamashita T, Sakai A, ★Sakai Y, Kagaya T, Yamashita T, Honda M, Kaneko S. Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma. Hepatology. 2011 Apr;53(4):1206-16. doi: 10.1002/hep.24149.
  125. Honda M, Takehana K, Sakai A, Tagata Y, Shirasaki T, Nishitani S, Muramatsu T, Yamashita T, Nakamoto Y, Mizukoshi E, ★Sakai Y, Yamashita T, Nakamura M, Shimakami T, Yi M, Lemon SM, Suzuki T, Wakita T, Kaneko S; Hokuriku Liver Study Group. Malnutrition impairs interferon signaling through mTOR and FoxO pathways in patients with chronic hepatitis C. Gastroenterology. 2011 Jul;141(1):128-40, 140.e1-2. doi: 10.1053/j.gastro.2011.03.051.
  126. Wada T, Sakai N, ★Sakai Y, Matsushima K, Kaneko S, Furuichi K. Involvement of bone-marrow-derived cells in kidney fibrosis. Clin Exp Nephrol. 2011 Feb;15(1):8-13. doi: 10.1007/s10157-010-0372-2.
  127. Nakamoto Y, Mizukoshi E, Kitahara M, Arihara F, ★Sakai Y, Kakinoki K, Fujita Y, Marukawa Y, Arai K, Yamashita T, Mukaida N, Matsushima K, Matsui O, Kaneko S. Prolonged recurrence-free survival following OK432-stimulated dendritic cell transfer into hepatocellular carcinoma during transarterial embolization. Clin Exp Immunol. 2011 Feb;163(2):165-77. doi: 10.1111/j.1365-2249.2010.04246.x.
  128. Kakinoki K, Nakamoto Y, Kagaya T, Tsuchiyama T, ★Sakai Y, Nakahama T, Mukaida N, Kaneko S. Prevention of intrahepatic metastasis of liver cancer by suicide gene therapy and chemokine ligand 2/monocyte chemoattractant protein-1 delivery in mice. J Gene Med. 2010 Dec;12(12):1002-13. doi: 10.1002/jgm.1528.
  129. Sunagozaka H, Honda M, Yamashita T, Nishino R, Takatori H, Arai K, Yamashita T, ★Sakai Y, Kaneko S. Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma. Int J Cancer. 2011 Oct 1;129(7):1576-85. doi: 10.1002/ijc.25830.
  130. 中出祐介, 藤村政樹, 大倉徳幸, 早稲田優子, 山崎宏人, 犬塚賀奈子, 池田博子, 大江宏康, 南部裕子, 高村利治, ★酒井佳夫, 和田隆志.　体プレスチモグラフ法による肺気量分画測定が診断に有用であった同種造血幹細胞移植後閉塞性細気管支炎の１例　臨床病理　第58巻 第9号p.906-911（平成２２年９月）
  131. 中出祐介, 藤村政樹, 南部裕子, 長原三輝雄, 大江宏康, 高村利治, ★酒井佳夫, 和田隆志. 呼吸機能検査システムの有用性と今後の課題　医療情報の電子化・共有化に向けての一考察　医学検査 : 日本臨床衛生検査技師会誌　2010 vol.59(9)、p.1057(35) – p.1062(40).
  132. Honda M, Nakamura M, Tateno M, Sakai A, Shimakami T, Shirasaki T, Yamashita T, Arai K, Yamashita T, ★Sakai Y, Kaneko S. Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C. J Hepatol. 2010 Nov;53(5):817-26. doi: 10.1016/j.jhep.2010.04.036.
  133. 中田晶子,　南部裕子,　中出祐介,　高村利治,　金田礼三,　岩佐和夫,　★酒井佳夫,　和田隆志.　脳神経生理検査データネットワークシステム導入の効果　医学検査 : 日本臨床衛生検査技師会誌　2010 vol.59(No.7)、p.873(41)-876(44).
  134. 吉谷久子, 竹本賢一, 前河晶子, 高村利治, ★酒井佳夫, 和田隆志. HCV RNA測定試薬コバスTaqManHCV「オート」の基礎的検討とその有用性　2010日本臨床検査自動化学会会誌vol.35(3) p.328-331.
  135. Honda M, ★Sakai Y, Yamashita T, Yamashita T, Sakai A, Mizukoshi E, Nakamoto Y, Tatsumi I, Miyazaki Y, Tanno H, Kaneko S; Hokuriku Liver Study Group. Differential Gene Expression Profiling in Blood from Patients with Digestive System Cancers. Biochem Biophys Res Commun. 2010 Sep 10;400(1):7-15. doi: 10.1016/j.bbrc.2010.07.123.
  136. Shirasaki T, Honda M, Mizuno H, Shimakami T, Okada H, ★Sakai Y, Murakami S, Wakita T, Kaneko S. La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication. J Infect Dis. 2010 Jul 1;202(1):75-85. doi: 10.1086/653081.
  137. Honda M, Sakai A, Yamashita T, Nakamoto Y, Mizukoshi E, ★Sakai Y, Yamashita T, Nakamura M, Shirasaki T, Horimoto K, Tanaka Y, Tokunaga K, Mizokami M, Kaneko S; Hokuriku Liver Study Group. Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C. Gastroenterology. 2010 Aug;139(2):499-509. doi: 10.1053/j.gastro.2010.04.049.
  138. Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, ★Sakai Y, Takamura T, Horimoto K, Takamura M. Altered hepatic gene expression profiles associated with myocardial ischemia. Circ Cardiovasc Genet. 2010 Feb;3(1):68-77. doi: 10.1161/CIRCGENETICS.108.795484.
  139. Steel J, Ramlogan C, Yu P, ★Sakai Y, Forni G, Waldmann T, Morris J. Interleukin-15 and its Receptor Augment Dendritic Cell Vaccination Against the neu Oncogene Through the Induction of neu Antibodies Partially Independent of CD4 Help. Cancer Res. 2010 Feb 1;70(3):1072-81. doi: 10.1158/0008-5472.CAN-09-1301. Epub 2010 Jan 19.
  140. Komura T, ★Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S. CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes. Diabetes. 2010 Mar;59(3):634-43. doi: 10.2337/db09-0659.
  141. Ura S, Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Sunakozaka H, ★Sakai Y, Horimoto K, Kaneko S. Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma. Hepatology. 2009 Apr;49(4):1098-112. doi: 10.1002/hep.22749.
  142. 健診を契機に発見された非機能性膵内分泌腫瘍の2例. 丹尾 幸樹, 島上 哲朗, 山下 太郎, 加賀谷 尚史, ★酒井 佳夫, 山下 竜也, 水腰 英四郎, 酒井 明人, 中本 安成, 本多 政夫, 金子 周一, 北川 裕久, 萓原 正都, 太田 哲生, 全 陽. 日本消化器病学会雑誌. 2009 年 106 巻 4 号 p. 560-568.
  143. ★Sakai Y, Honda M, Fujinaga H, Tatsumi I, Mizukoshi E, Nakamoto Y, Kaneko S: Common Transcriptional Signature of Tumor-infiltrating Mononuclear Inflammatory Cells and Peripheral Blood Mononuclear Cells in Hepatocellular Carcinoma Patients. Cancer Res. 2008 Dec 15;68(24):10267-79. doi: 10.1158/0008-5472.CAN-08-0911.
  144. Tsuchiyama T, Nakamoto Y, ★Sakai Y, Mukaida N, Kaneko S. Optimal amount of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy against hepatocellular carcinoma by M1 macrophage activation. Cancer Sci. 2008 Oct;99(10):2075-82. doi: 10.1111/j.1349-7006.2008.00951.x.
  145. Park JM, Terabe M, Steel JC, Forni G, ★Sakai Y, Morris JC, Berzofsky JA. Therapy of advanced established murine breast cancer with a recombinant adenoviral ErbB-2/neu vaccine. Cancer Res. 2008 Mar 15;68(6):1979-87. doi: 10.1158/0008-5472.CAN-07-5688.
  146. Takamura T, Honda M, ★Sakai Y, Ando H, Shimizu A, Ota T, Sakurai M, Misu H, Kurita S, Matsuzawa-Nagata N, Uchikata M, Nakamura S, Matoba R, Tanino M, Matsubara K, Kaneko S. Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes. Biochem Biophys Res Commun. 2007 Sep 21;361(2):379-84.
  147. Wada T, Maeba H, Ikawa Y, Hashida Y, Okumura A, Shibata F, Tone Y, Inoue M, Koizumi S, Takatori H, ★Sakai Y, Kaneko S, Yachie A. Reactive peripheral blood plasmacytosis in a patient with acute hepatitis a. Int J Hematol. 2007 Apr;85(3):191-4
  148. Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, ★Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon. FEBS Lett. 2007 May 15;581(10):1983-7.
  149. Tsuchiyama T, Nakamoto Y, ★Sakai Y, Marukawa Y, Kitahara M, Mukaida N, Kaneko S. Prolonged, NK Cell-Mediated Antitumor Effects of Suicide Gene Therapy Combined with Monocyte Chemoattractant Protein-1 against Hepatocellular Carcinoma. J Immunol. 2007 Jan 1;178(1):574-83.
  150. Nakamoto Y, Mizukoshi E, Tsuji H, ★Sakai Y, Kitahara M, Arai K, Yamashita T, Yokoyama K, Mukaida N, Matsushima K, Matsui O, Kaneko S. Combined therapy of transcatheter hepatic arterial embolization with intratumoral dendritic cell infusion for hepatocellular carcinoma: clinical safety.  Clin Exp Immunol. 2007 Feb;147(2):296-305.
  151. Yamashita T, Arai K, Sakai A, Mizukoshi E, ★Sakai Y, Kagaya T, Nakamoto Y, Honda M, Wada T, Yokoyama H, Kaneko S. Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chornic hepatitis C: preliminary study. Hepatol Res. 2006 Nov;36(3):167-75.
  152. Kagaya T, Nakamoto Y, ★Sakai Y, Tsuchiyama T, Yagita H, Mukaida N, Kaneko S. Monocyte Chemoattractant protein-1 gene delivery enhances antitumor effects of herpes simplex virus thymidine kinase/ganciclovir system in a model of colon cancer. Cancer Gene Ther. 2006 Apr;13(4):357-66.
  153. Park JM, Terabe M, ★Sakai Y, Munasinghe J, Forni G, Morris JC, Berzofsky JA.　 Early Role of CD4+ Th1 Cells and Antibodies in HER-2 Adenovirus Vaccine Protection against Autochthonous Mammary Carcinomas. J Immunol. 2005 Apr 1;174(7):4228-36.
  154. Kobayashi H, Dubois S, Sato N, Sabzevari H, ★Sakai Y, Waldmann TA, Tagaya Y. Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance. Blood. 2005 Jan 15;105(2):721-7.
  155. ★Sakai Y, Morrison BJ, Burke JD, Park JM, Terabe M, Janik JE, Forni G, Berzofsky JA, Morris JC. Vaccination by Genetically Modified Dendritic Cells Expressing a Truncated neu Oncogene Prevents Development of Breast Cancer in Transgenic Mice. Cancer Res. 2004 Nov 1;64(21):8022-8.
  156. Kobayashi H, Kawamoto S, ★Sakai Y, Choyke PL, Star RA, Brechbiel MW, Sato N, Tagaya Y, Morris JC, Waldmann TA. Lymphatic drainage imaging of breast cancer in mice by micro-magnetic resonance lymphangiography using a nano-size paramagnetic contrast agent. J Natl Cancer Inst. 2004 May 5;96(9):703-8.
  157. Tsuchiyama T, Kaneko S, Nakamoto Y, Sakai Y, Honda M, Mukaida N, Kobayashi K. Enhanced antitumor effects of a bicistronic adenovirus vector expressing both herpes simplex virus thymidine kinase and monocyte chemoattractant protein-1 against hepatocellular carcinoma. Cancer Gene Ther. 2003 Apr;10(4):260-9.
  158. ★Sakai Y, Kaneko S, Nakamoto Y, Kagaya T, Mukaida N, Kobayashi K. Enhanced Anti-tumor Effects of Herpes Simplex Virus Thymidine Kinase / Ganciclovir System by Codelivering Monocyte Chemoattractant Protein-1 in Hepatocellular Carcinoma. Cancer Gene Ther. 2001 Oct;8(10):695-704.
  159. ★Sakai Y, Kaneko S, Sato Y, Kanegae Y, Tamaoki T, Saito I, Kobayashi K. Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with α-fetoprotein promoter and Cre/loxP system. J Virol Methods. 2001 Mar;92(1):5-17.
  160. Sato Y, Tanaka K, Lee G, Kanegae Y, ★Sakai Y, Kaneko S, Nakabayashi H, Tamaoki T, Saito I.. Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector. Biochem Biophys Res Commun. 1998 Mar 17;244(2):455-62.
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